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Table 4 Correlation between anti-CCP, leptin, sLepR, or leptin/sLep, and adiposity, inflammatory and metabolic markers

From: Serum leptin and serum leptin/serum leptin receptor ratio imbalance in obese rheumatoid arthritis patients positive for anti-cyclic citrullinated peptide antibodies

  Anti-CCP sLep sLepR sLep/sLepR
Measurement R r r r
P P P P
BMI, kg/m2 −0.154 0.494 −0.472 0.556
0.221 <0.001 <0.001 <0.001
Body fat mass, % −0.174 0.570 −0.458 0.587
0.166 <0.001 <0.001 <0.001
ESR, mm/h 0.137 0.257 −0.259 0.355
0.294 0.033 0.059 <0.001
CRP, mg/L 0.293 0.063 −0.177 0.092
0.021 0.597 0.205 0.515
sLep, ng/Ml −0.004 - −0.557 0.940
0.977   <0.001 <0.001
sLepR, ng/Ml −0.134 0.613 - −0.740
0.354 <0.001   <0.001
Insulin μUI/Ml −0.083 0.427 −0.148 0.314
0.567 0.001 0.286 <0.001
HOMA-IR −0.091 0.416 −0.072 0.236
0.533 0.002 0.607 0.092
  1. Pearson r coefficient was calculated. Anti-CCP anti cyclic citrullinated peptide antibodies, BMI body mass index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, DAS-28 disease activity index in 28 joints, sLepR soluble leptin receptor, FM fat mass, HOMA-IR, homeostatic model assessment-insulin resistance. RF rheumatoid factor