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Table 4 Correlation between anti-CCP, leptin, sLepR, or leptin/sLep, and adiposity, inflammatory and metabolic markers

From: Serum leptin and serum leptin/serum leptin receptor ratio imbalance in obese rheumatoid arthritis patients positive for anti-cyclic citrullinated peptide antibodies

 

Anti-CCP

sLep

sLepR

sLep/sLepR

Measurement

R

r

r

r

P

P

P

P

BMI, kg/m2

−0.154

0.494

−0.472

0.556

0.221

<0.001

<0.001

<0.001

Body fat mass, %

−0.174

0.570

−0.458

0.587

0.166

<0.001

<0.001

<0.001

ESR, mm/h

0.137

0.257

−0.259

0.355

0.294

0.033

0.059

<0.001

CRP, mg/L

0.293

0.063

−0.177

0.092

0.021

0.597

0.205

0.515

sLep, ng/Ml

−0.004

-

−0.557

0.940

0.977

 

<0.001

<0.001

sLepR, ng/Ml

−0.134

0.613

-

−0.740

0.354

<0.001

 

<0.001

Insulin μUI/Ml

−0.083

0.427

−0.148

0.314

0.567

0.001

0.286

<0.001

HOMA-IR

−0.091

0.416

−0.072

0.236

0.533

0.002

0.607

0.092

  1. Pearson r coefficient was calculated. Anti-CCP anti cyclic citrullinated peptide antibodies, BMI body mass index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, DAS-28 disease activity index in 28 joints, sLepR soluble leptin receptor, FM fat mass, HOMA-IR, homeostatic model assessment-insulin resistance. RF rheumatoid factor