Fig. 4
From: Interleukin-6-dependent influence of nociceptive sensory neurons on antigen-induced arthritis
In vitro cytokine expression profiles of lymphocytes isolated on day 3 of AIA from SNS-gp130flox/flox and SNS-gp130−/− mice in vitro. a. Cytokine levels in supernatants of anti-CD3-stimulated spleen cells (IL-2, p = 0.039). b. Cytokine levels in supernatants of anti-CD3-stimulated lymph node cells. c. Cytokine levels in supernatants of antigen (mBSA)-specific restimulated spleen cells (IL-17, p = 0.035; IFNγ, p = 0.034). d. Cytokine levels in supernatants of antigen (mBSA)-specific restimulated lymph node cells (IFNγ, p = 0.038). Specifications in brackets define the dilution of the cytokine values. Values are mean ± SEM, n = 8–10 per group. IFNγ interferon-γ, IL interleukin, mBSA methylated bovine serum albumin