Fig. 2

Anti-CarP antibodies in relation to ACPA and IgM-RF in RA and other forms of early arthritis. a Receiver operator curve and AUC analysis of dichotomous data of anti-CarP antibodies in the whole cohort. b Distribution of positivity for anti-CarP antibodies, anti-CCP2 antibodies and IgM-RF in the patients diagnosed with RA. c Distribution of these autoantibodies in the patients diagnosed with the non-RA forms of early arthritis. Both b and c are for all individuals for whom data on anti-CarP and CCP2 and RF were available (n = 934 for RA and n = 780 for non-RA). d Odds ratios for having the diagnosis RA based on the presence of one, two or three autoantibodies relative to having zero autoantibodies. ACPA Anti-citrullinated protein antibodies, Anti-CarP Anti-carbamylated protein, AUC Area under the curve, IgM-RF Immunoglobulin M-rheumatoid factor, RA Rheumatoid arthritis