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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Effect of abatacept on the immunogenicity of 23-valent pneumococcal polysaccharide vaccination (PPSV23) in rheumatoid arthritis patients

Fig. 2

a Comparison of post-vaccination GMC responses in patients receiving DMARDs (control), MTX and ABT. Percentages of patients with an increase in 6B or 23F serotype-specific IgG concentration greater than two-fold are shown. There was a significant difference in the 6B serotype-specific IgG response rates between control and ABT groups (p = 0.034). Data were compared using the Pearson chi-square test. b Comparison of post-vaccination OIs responses in patients receiving DMARDs (control), MTX and ABT. Percentage of patients with an increase in OIs for serotypes 6B or 23F greater than ten-fold are shown. There was no significant difference in the response rates among control, MTX and ABT groups. GMC geometric mean concentration, DMARDS disease modifying anti-rheumatic drugs, MTX methotrexate, ABT abatacept, OIs opsonization index

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