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Table 2 Adjusted mean differences in clinical outcomes over the first 2 years between nulliparous and parous women

From: Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material

  DAS28 HAQ
  Beta (95 % CI), p-value Beta (95 % CI), p-value
All patients 0.11 (−0.05 to 0.27), p = 0.17 0.06 (−0.00 to 0.13), p = 0.07
ACPA negative   
 Aged 18–44 1.17 (0.65 to 1.68), p < 0.001 0.43 (0.20 to 0.66), p < 0.001
 Aged 45–70 −0.26 (−0.62 to 0.09), p = 0.14 −0.06 (−0.20 to 0.09), p = 0.46
ACPA positive   
 Aged 18–44 0.06 (−0.25 to 0.38), p = 0.69 0.07 (−0.05 to 0.19), p = 0.27
 Aged 45–70 0.08 (−0.20 to 0.36), p = 0.57 0.02 (−0.10 to 0.14), p = 0.70
  1. Mixed models adjusted for age at inclusion in the Epidemiological Investigation of Rheumatoid Arthritis (EIRA), with nulliparous women as reference. ACPA Anti-citrullinated protein antibody, CI confidence interval, DAS28 Disease activity score 28, HAQ Health assessment questionnaire