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Table 3 Multivariable linear regression analysis assessing AS as an independent predictor of BMD, and bone microarchitecture

From: Alterations of bone mineral density, bone microarchitecture and strength in patients with ankylosing spondylitis: a cross-sectional study using high-resolution peripheral quantitative computerized tomography and finite element analysis

HRpQCT Radius Tibia
βa 95 % CI p value Adj. R 2 βa 95 % CI p value Adj. R 2
Trabecular vBMD −15.1 −33.3 to –3.2 0.105 0.184 −17.2 −35.3 to –1.5 0.071 0.094
Cortical vBMD −34.3 −62.8 to –7.9 0.011 0.160 −28.15 −55.1 to –5.4 0.018 0.096
Total vBMD −41.6 −71.0 to –12.1 0.006 0.087 −28.13 −51.7 to 4.5 0.020 0.256
Trabecular number –0.088 –0.244 to –0.068 0.268 0.070 –0.065 −0.343 to 0.113 0.471 0.063
Trabecular thickness –0.004 –0.008 to 0.001 0.087 0.217 –0.004 –0.010 to 0.003 0.260 0.001
Trabecular separation 0.052 0.011–0.115 0.105 0.072 0.060 –0.017 to 0.137 0.128 0.063
BV/TV (%) –0.013 –0.028 to –0.003 0.106 0.184 –0.014 –0.030 to –0.001 0.070 0.094
Cortical thickness –0.101 –0.163 to –0.039 0.002 0.202 –0.060 –0.116 to 0.004 0.035 0.381
Cortical porosity 0.006 0.001–0.010 0.016 0.326 0.013 0.002–0.023 0.016 0.323
Stiffness –0.226 –0.384 to –0.069 0.005 0.055 –0.160 –0.333 to 0.013 0.069 0.081
Stress −5.7 −9.61 to –1.7 0.005 0.055 −4.0 −8.3 to 0.24 0.064 0.082
  1. aBeta coefficient represents the difference between patients with AS (n = 53) and subjects without AS (n = 85), and subjects without AS are the reference category. The model was adjusted for differences in age and sex
  2. Adj. adjusted, AS ankylosing spondylitis, BMD bone mineral density, BV/TV bone volume/trabecular volume, CI confidence interval, HRpQCT high-resolution peripheral quantitative computerized tomography, vBMD volumetric bone mineral density
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