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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult

Fig. 4

Study 2. Histological stains for cellularity (H&E), GAG (Safranin 0), bulk collagen (Picrosirius Red), and collagen II (Alexa Fluor 488) distribution for juvenile bovine constructs exposed to IL-1α insult in the (b, f, j, n) absence of or after (c, g, k, o) immediate and (d, h, i, p) delayed insult schemes (0.5 ng/mL). Scale bar = 0.5 mm. Arrows indicate depleted ECM matrix. ECM extracellular matrix, GAG glycosaminoglycan, H&E hematoxylin and eosin, IL-1 interleukin-1

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