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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Systematic review and meta-analysis of serious infections with tofacitinib and biologic disease-modifying antirheumatic drug treatment in rheumatoid arthritis clinical trials

Fig. 4

Risk differences for biologic DMARDs and tofacitinib versus placebo across RCTs in DMARD-IR patients. Studies were predominantly on background methotrexate. BID twice daily, CI confidence interval, DMARD(−IR) disease-modifying antirheumatic drug(−inadequate responder), RCT randomized controlled trial, TNFi tumor necrosis factor inhibitors

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