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Table 4 Serum biochemical factor levels of control or LBP subjects (geometric mean ± corresponding standard error, pg/ml)

From: Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases

Biochemical factor

Control levels (pg/ml)

LBP levels (ESI & Surgery, pg/ml)

p-value

IL-1β

0.028 ± 0.004

0.033 ± 0.003

0.34

IL-2

0.14 ± 0.026

0.068 ± 0.006

0.0005***

IL-4

0.012 ± 0.002

0.018 ± 0.001

0.012*

IL-6

0.37 ± 0.057

0.52 ± 0.041

0.049*

IL-8

12.49 ± 2.34

10.11 ± 0.95

0.32

IL-10

0.25 ± 0.040

0.23 ± 0.018

0.71

IL-12p70

0.075 ± 0.012

0.089 ± 0.007

0.39

IL-13

0.29 ± 0.039

0.34 ± 0.022

0.39

TNF-α

2.05 ± 0.21

2.47 ± 0.13

0.11

IFN-γ

5.06 ± 0.97

4.86 ± 0.47

0.86

MMP-1

26,264 ± 3,828

14,923 ± 1,088

0.0008**

MMP-3

14,612 ± 1,862

15,440 ± 984

0.70

MMP-9

169,618± 21,665

151,437 ± 9,679

0.43

  1. Statistical analysis (p-value) of differences in levels between control and LBP participants was performed using ANCOVA controlling for age and gender effects
  2. *p<0.05, **p<0.005, ***p<0.0005