Arthritis Research & Therapy

Table 6 Geometric Mean ± corresponding standard error (pg/ml) of serum biochemical factors are reported and compared based on diagnostic groups

From: Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases

		DH	Other Dx	p-value
Cytokines (pg/mL)
IL-1β		0.033 ± 0.004	0.037 ± 0.005	0.52
IL-2		0.067 ± 0.011	0.064 ± 0.013	0.83
IL-4		0.017± 0.002	0.019 ± 0.003	0.30
IL-6		0.47 ± 0.060	0.74 ± 0.116	0.014*
IL-8		9.57 ± 1.48	12.68 ± 2.43	0.20
IL-10		0.22 ± 0.030	0.27 ± 0.046	0.25
IL-12p70		0.11 ± 0.015	0.079 ± 0.014	0.14
IL-13	Male	0.43 ± 0.059	0.28 ± 0.050	0.046*
IL-13	Female	0.32 ± 0.037	0.44 ± 0.067	0.081
TNF-α		2.33 ± 0.20	2.80 ± 0.30	0.14
IFN-γ		4.74 ± 0.73	6.16 ± 1.19	0.23
MMPs (pg/ml)
MMP-1		15,918 ± 1911	17,730 ± 2650	0.53
MMP-3		16,471 ± 1799	16,304 ± 2219	0.95
MMP-9		154,271 ± 15,925	145,514 ± 18,705	0.69

DH: disc herniation; Other Dx: other diagnoses include spinal stenosis (SS) and degenerative disc disease (DDD). Statistical analysis (p-value) of differences between DH and Other Dx was performed with ANCOVA, controlling for effects of age, gender and OA history
*p<0.05.

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