Fig. 2
From: Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β
Hedgehog pathway modulation does not influence cartilage degradation in bovine explants. The sulphated glycosaminoglycans (sGAG) release for explants treated with r-Ihh (a) and cyclopamine (b) shown at 24-hour intervals and cumulatively over the 72-hour culture period as compared to untreated controls. All data are displayed as mean sGAG release, normalised to the untreated controls at the same time point, with standard deviation error bars (n = 9 from three separate donors). r-Ihh recombinant Ihh