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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Overexpression of TLR2 and TLR9 on monocyte subsets of active rheumatoid arthritis patients contributes to enhance responsiveness to TLR agonists

Fig. 2

Toll-like receptor2 (TLR2) expression levels are increased in blood and synovial monocyte subsets of rheumatoid arthritis (RA) patients. a Flow cytometry analysis of TLR2 expression on blood monocyte subsets from healthy controls and RA patients. TLR2 expression for synovial monocyte subsets is also shown for RA patients. TLR2-positive cells appear in green (P1), blue (P2) or purple (P3). Gray histograms represent internal negative controls. Data are cell populations of representative donors. b TLR2 expression on each blood monocyte subset of healthy controls and RA patients is presented as mean fluorescence intensity (MFI) (mean ± standard error of the mean (SEM)). Black bars healthy donors, gray bars RA patients. c TLR2 expression in the monocyte subsets from synovial fluids of RA patients is presented as MFI (mean ± SEM). Striped bars RA patient synovial fluids: *p ≀0.05 and **p ≀0.01

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