Fig. 3

Increased level of toll-like receptor 9 (TLR9) on circulating and synovial monocyte subsets of rheumatoid arthritis (RA) patients. a Flow cytometry analysis of TLR9 expression on blood monocyte subsets from healthy controls and RA patients. TLR9 expression for synovial monocyte subsets is also shown for RA patients. TLR9 expression appears in green (P1), blue (P2) or purple (P3). Gray histograms represent internal negative controls. Data are cell populations of representative donors. b TLR9 expression on blood monocyte subsets from healthy controls and RA patients are presented as mean fluorescence intensity (MFI) (mean ± standard error of the mean (SEM)). Black bars healthy donors, gray bars RA patients. c TLR9 expression in the monocyte subsets of RA patient synovial fluids is presented as MFI (mean ± SEM). Striped bars RA patient synovial fluids: *p ≤0.05