Fig. 2
From: Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis
Effect of soluble biglycan (sBGN) on the expression of matrix metalloproteinase (MMP)-1, MMP-3, MMP-9 and MMP-13 as well as interleukin (IL)-6 and IL-8 proteins. sBGN leads to the upregulation chondrocyte-mediated production of major catabolic markers known in osteoarthritis. sBGN-induced concentration levels compared with controls did not reach the statistical significance level <0.05. The results are expressed mean ± SD. Samples were run as technical duplicates, and each experiment was done using samples from three different donors (biological replicates)