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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat

Fig. 2

a–i The effect of tested drugs (alendronate, clonidine, curcumin, fluocinolone, meloxicam, tacrolimus, tranilast, triamcinolone hexacetonide, and withaferin) on osteoclast differentiation and resorption. The lowest concentrations tested are shown; additional data is provided in Additional file 1. Following one-way analysis of variance, pairwise comparisons with the tumor necrosis factor control were made using a standard two-tailed t test. *p ≤ 0.05, **p ≤ 0.001. RANK receptor activator of NF-κB

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