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Table 1 Demographic and clinical features of SSc patients in the discovery and replication cohorts

From: Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients

 

Discovery (n = 1486)

Replication (n = 1085)

Female

1307 (88.0 %)

934 (86.1 %)

Mean age ± years

54.5 ± 12.9 y

56.1 ± 12.8 y

Diffuse SSc

505 (34.0 %)

403 (37.1 %)

Disease duration

10.1 ± 8.7 y

10.9 ± 9.6 y

ACA

425 (28.6 %)

340 (31.3 %)

ATA

238 (16.0 %)

180 (16.6 %)

SSc-ILD

  

 Yes

185 (65.6 %)

313 (61.9 %)

 No

97 (34.4 %)

193 (38.1 %)

  1. ACA anti-centromere antibody, ATA anti-topoisomerase 1 antibody, SSc systemic sclerosis, ILD interstitial lung disease