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Table 1 Descriptive data at baseline (T0) for 950 patients and at 5-year follow up (T5) in 726 of the patients diagnosed with early rheumatoid arthritis

From: Co-morbidity in patients with early rheumatoid arthritis - inflammation matters

Characteristics

Values

Age at onset of symptoms, years

55.6 (14.4)

Female/male, T0

649/301 (68.3/31.7)

Duration of symptoms at T0, months

6.7 (3.5)

RF+

75.3

ANA+

22.0

ACPA+

69.0

HLA-SE+

58.0

Disease activity and severity at T0

 

ESR, mm/h

30.1 (23.2)

CRP, mg/L

20.7 (24.3)

HAQ

0.86 (0.6)

Tender joint count

6.4 (5.7)

Swollen joint count

7.0 (5.2)

VAS pain, mm

43.4 (25.7)

VAS global, mm

44.4 (25.7)

AUC DAS28, 6 months

25.1 (7.2)

AUC DAS28, 12 months

46.2 (13.4)

AUC DAS28, 24 months

86.5 (25.6)

Ex-RA ≤ T5

4.9

Nodules ≤ T5

16.4

Smoking ever, T0

65.8

Treatments

 

DMARDs within 3 months after T0

90.1

DMARDs ever ≤ T5

97.8

Methotrexate ever ≤ T5

86.9

Biological treatment ever ≤ T5

16.5

Time without DMARDs from symptom onset, months

6.8 (4.9)

Time without DMARDs T0–T5, months

8.4 (15.7)

NSAIDs ever ≤ T5

84.0

Cox-2 inhibitors ever ≤ T5

26.5

Corticosteroids T0–T5, months

22.2 (23.8)

Corticosteroids ever ≤ T5

71.0

  1. Mean(SD), number or percent. RF rheumatoid factor, ANA anti-nuclear antibody, ACPA anti-citrullinated protein/peptide antibody (analyzed as anti-CCP2), HLE-SE human leucocyte antigen-shared epitope, ESR erythrocyte sedimentation rate, CRP C-reactive protein, HAQ health assessment questionnaire, AUC area under curve, DAS28 disease activity score in 28 joints, Ex-RA extra articular manifestations of RA, DMARDs disease modifying anti-rheumatic drugs, NSAIDs non-steroid anti-inflammatory drugs, Cox-2 cyclo oxygenase 2inhibitors