Table 3 Diagnostic accuracy for SLE of the PNC assay, CLIFT, and their combined positivity in MRG patients

Sensitivity (95 % CI)

0.20 (0.12–0.37)

0.32 (0.22–0.44)

0.15 (0.09–0.26)

Specificity (95 % CI)

0.95 (0.93–0.97)

0.95 (0.93–0.97)

0.99 (0.97–0.99)

PPV (95 % CI)

0.37 (0.23–0.54)

0.48 (0.34–0.62)

0.67 (0.42–0.85)

LR+ (95 % CI)

4.22 (2.24–7.96)

6.52 (3.83–11.10)

14.28 (5.04–40.46)

LR− (95 % CI)

0.84 (0.74–0.95)

0.71 (0.60–0.84)

0.86 (0.77–0.95)