Skip to main content

Table 1 Demographic and disease characteristics of patients with and without fibromyalgia

From: Evaluation of the impact of fibromyalgia in disease activity and treatment effect in spondyloarthritis

  Total number of patients Fibromyalgia+ Fibromyalgia– P
(n = 196) (n = 42) (n = 154)
Age, years 43.0 (12.6) 41.4 (10.2) 43.4 (13.13) 0.21
Gender, female 59 (30.1 %) 17 (40.5 %) 42 (27.3 %) 0.10
Age at disease onset, years 29.9 (11.9) 28.7 (9.3) 30.2 (12.5) 0.40
Smoking status, ever smoked 106 (55.8 %) 23 (56.1 %) 83 (55.7 %) 0.96
HLA B27-positive 157 (82.2 %) 35 (83.3 %) 122 (81.9 %) 0.83
Radiographic sacroiliitis 134 (70.2 %) 27 (67.5 %) 107 (70.9 %) 0.68
Magnetic resonance imaging evidence of inflammatory lesions of the sacroiliac joints 88 (58.3 %) 20 (54.1 %) 68 (59.7 %) 0.55
Raised C-reactive protein* 39 (22.3 %) 8 (20.0 %) 31 (23.0 %) 0.69
Past history of, or current arthritis 72 (36.7 %) 12 (28.6 %) 60(39 %) 0.22
Past history of, or current enthesitis 85 (43.4 %) 25 (59.5 %) 60 (39 %) 0.01
Bath Ankylosing Spondylitis Disease Activity Index total (0–10) 3.0 (2.2) 4.7 (2.3) 2.6 (1.9) <0.01
Global visual analog scale (0–10) 3.6 (2.8) 5.9 (2.4) 3.0 (2.5) <0.01
Bath Ankylosing Spondylitis Functional Index (range 0–10) 2.6 (2.7) 4.8 (2.7) 2.0 (2.3) <0.01
History of depression 42 (23.2 %) 16 (41.0 %) 26 (18.3 %) <0.01
Past or current intake of psychotropic medications** or strong opioids 82 (41.8 %) 28 (66.7 %) 54 (35.1 %) <0.01
Past or current intake of psychotropic medications or strong opioids or history of depression 82 (41.8 %) 28 (66.7 %) 54 (35.1 %) <0.01
Non-steroidal anti-inflammatory drug intake, ever 193 (99.0 %) 42 (100.0 %) 151 (98.7 %) 1.00
Synthetic disease-modifying antirheumatic drug use, ever 104 (53.1 %) 23 (54.8 %) 81 (52.6 %) 0.80
  1. All results are presented as mean ± SD for continuous variables or number (%) for categorical variables. Fibromyalgia + was defined as a Fibromyalgia Rapid Screening Tool (FiRST) score ≥5/6. * ≥ 6 mg/L; **myorelaxants, antidepressants or anxiolytics