Fig. 2
From: MMP-3 as a predictor for structural remission in RA patients treated with MTX monotherapy
Cumulative probability plots for the change in van der Heijde modified total Sharp score per year (ΔTSS). Patient subgroups corresponding to structural remission (REM), radiographic evidence of progression (ΔTSS >3), or radiographic evidence of rapid progression (RRP) are indicated. Bio indicates a patient who began new treatment with a biologic agent. Ch indicates a patient who moved to another hospital because of inactive disease but continued methotrexate (MTX) treatment. Inf indicates a patient who developed infection, mandibular myelitis, and thus discontinued MTX treatment. Liv indicates a patient who had abnormal liver tests and thus discontinued MTX treatment. IP indicates a patient who developed interstitial pneumonitis and thus discontinued MTX treatment. St indicates a patient who developed stomatitis and thus discontinued MTX treatment