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Table 3 Correlations between DXR-BMD and radiographic scores in the csDMARD-to-TNFI cohort

From: Establishment of age- and sex-adjusted reference data for hand bone mass and investigation of hand bone loss in patients with rheumatoid arthritis treated in clinical practice: an observational study from the DANBIO registry and the Copenhagen Osteoarthritis Study

 

DXR-BMD status

 

Hand bone loss

n =135

Pre-baseline

Baseline

Follow-up

csDMARD period

TNFI period

JSN

–0.42 (<0.001)

–0.41 (<0.001)

–0.37 (<0.001)

JSN change

–0.09 (0.27)

–0.18 (0.002)

ES

–0.46 (<0.001)

–0.48 (<0.001)

–0.47 (<0.001)

ES change

–0.19 (0.02)

–0.13 (0.01)

TSS

–0.47 (<0.001)

–0.47 (<0.001)

–0.45 (<0.001)

TSS change

–0.21 (0.01)

–0.25 (0.003)

  1. p values from Spearmans rho are shown in parentheses
  2. csDMARD Conventional synthetic disease-modifying anti-rheumatic drug, DXR-BMD Bone mineral density estimated by digital x-ray radiogrammetry, ES Erosion score, JSN Joint space narrowing, TNFI Tumour necrosis factor alpha inhibitors, TSS Total Sharp score