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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Bone marrow lesions detected by specific combination of MRI sequences are associated with severity of osteochondral degeneration

Fig. 4

Micro-computed tomography bone analysis (a), subchondral plate, thickness and surface of closed pores; subchondral trabecular bone, bone volume fraction and structural model index. Bone turnover in subchondral plate (b), osteoid volume over tissue volume, volume of osteoid, osteoid surface over tissue volume and thickness of osteoid. Bone turnover in trabecular bone (c), osteoid volume over tissue volume, volume of osteoid, erosion surface over bone surface and thickness of osteoid. Represented graphically for specimens with no bone marrow lesions evident (No BML), bone marrow lesions evident only in fast spin-echo proton density-weighted (PDFS) sequences (BML 1), and bone marrow lesions evident in both PDFS and T1-weighted sequences (BML 2): *p = 0.05, **p = 0.005, ***p = 0.0005. BV bone volume, TV tissue volume, OV osteoid volume, OS osteoid surface, O.Th osteoid thickness, ES erosion surface, BS bone surface

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