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Table 2 Histological findings in the no BML and BML groups

From: Bone marrow lesions detected by specific combination of MRI sequences are associated with severity of osteochondral degeneration

 

No BML (n = 12)

BML (1 + 2) (n = 44)

P value

TM, number/mm2 a

2 (2, 3)

3 (3, 4)

<0.0001

Vascular cones, number/mm2 b

0.12 ± 0.07

0.20 ± 0.12

0.004

Edema

  

0.006

 Score 1 (<5 %)

83 %

41 %

 Score 2 (5–14 %)

17 %

31.8 %

 Score 3 (15–24 %)

-

20.4 %

 Score 4 (25–50 %)

-

6.8 %

 Score 5 (>50 %)

-

-

Fibrosis

  

0.4

 Score 1 (<5 %)

75 %

66 %

 Score 2 (5–14 %)

25 %

16 %

 Score 3 (15–24 %)

-

11 %

 Score 4 (25–50 %)

-

7 %

 Score 5 (>50 %)

-

-

Necrosis

  

0.002

 Score 1 (<5 %)

33.1 %

9 %

 Score 2 (5–14 %)

66.6 %

41 %

 Score 3 (15–24 %)

-

41 %

 Score 4 (25–50 %)

-

6.8 %

 Score 5 (>50 %)

-

2.2 %

Th. wall Art., number/mm2 a

0.07 (0.06, 0.1)

0.2 (0.1, 0.4)

<0.0001

Fibrovascular c., number/mm2 a

0 (0 %)

0 (0, 0.2)

0.01

  1. aValues presented with median (25th, 75th percentiles). bValues presented with mean ± standard deviation. P values are for difference between the group with no bone marrow lesions (No BML) and the group with BML (BML 1 + BML 2). TM tidemark duplications, Vascular cones vascular cones penetrating from subchondral bone into calcified cartilage, Th. wall Art thick-walled arterioles present in marrow, Fibrovascular c. fibrovascular cystic formations