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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Increased caveolin-1 in intervertebral disc degeneration facilitates repair

Fig. 2

Effect of in vivo caveolin-1 (Cav-1) inactivation on extracellular matrix production of the murine nucleus pulposus (NP). Picrosirius red/Alcian Blue staining (a) and immunohistochemistry for collagen type II (b) on the NP of wild-type (WT) and Cav-1-null mice. GAGs and collagen type II are abundantly present in the extracellular matrix of Cav-1-null mice NPs, whereas they were present to a lesser extent in WT mice NPs. Bars indicate 100 μm. n = 4–9 per age group and condition (WT or Cav-1-null mice)

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