Fig. 2

Macroscopy and morphological assessments of male ephrin-B2 (EFNB2)^fl/fl and EFNB2^Col2knockout (KO) cartilage conditional mice. a Representative mascroscopic and histochemical results of EFNB2^fl/fl (n = 6) and EFNB2^Col2KO cartilage conditional (n = 6) mice at postnatal day zero (P0) (birth) showing that the latter displayed reduced growth and skeletal development. Arrow indicates thinner stained region in the EFNB2^Col2KO. Histograms show body weight (b) and length (c) of EFNB2^fl/fl and EFNB2^Col2KO cartilage conditional mice at P0 (n = 8 and n = 9, respectively), P15 (n = 10 and n = 8) and P21 (n = 13 and n = 11). d Morphometric analysis of long bone length of EFNB2^fl/fl and EFNB2^Col2KO cartilage conditional mice at P0 and P15 (n = 8–13). Data are expressed as mean ± standard error of the mean and P values were determined by Mann–Whitney U test