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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo

Fig. 3

Immunohistochemical localization of type II collagen, type X collagen and Safranin O in epiphyseal cartilage. Representative immunohistological sections of ephrin-B2 (EFNB2)fl/fl (n = 7) and EFNB2Col2knockout (KO) cartilage conditional (n = 7) mice at postnatal day zero (P0) (birth) for type II collagen (a-b), type X collagen (c-f) and Safranin O (g-l) of the entire epiphyseal cartilage. e, f Higher magnification of c and d. i, j Higher magnification of g and h. The secondary center of ossification at P15 is indicated by white arrows (k and l). a-f Slides were counterstained with methyl green. Original magnification × 250 (a-d, g, h, k, l) and × 400 (e, f, i, j). Scale bars at 100 μm (a, e, k)

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Arthritis Research & Therapy

ISSN: 1478-6362

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