Response criterion | Analysis | Number of patients | All | PLR | SLR | AE | Other | p Valuea | p Valueb |
---|---|---|---|---|---|---|---|---|---|
Patients with a clinical diagnosis of axSpA | |||||||||
ASDAS-ESR <2.1 | Response/tolerance | 184 | 28.8 | 11.1 | 38.9 | 26.2 | 38.9 | 0.01 | 0.002 |
ASDAS-ESR <2.1 | Per protocol | 124 | 42.7 | 21.7 | 50.8 | 35.5 | 63.6 | 0.04 | 0.02 |
ASDAS-ESR <1.3 | Response/tolerance | 184 | 14.7 | 4.4 | 21.5 | 9.5 | 22.2 | 0.03 | 0.01 |
ASDAS-ESR <1.3 | Per protocol | 124 | 21.8 | 8.7 | 28.8 | 12.9 | 36.4 | 0.07 | 0.08 |
ASAS-PR | Response/tolerance | 227 | 11.0 | 2.0 | 12.5 | 13.7 | 16.7 | 0.08 | 0.04 |
ASAS-PR | Per protocol | 146 | 17.1 | 4.2 | 17.4 | 18.4 | 33.3 | 0.12 | 0.17 |
Patients fulfilling the ASAS axSpA classification | |||||||||
ASDAS-ESR <2.1 | Response/tolerance | 148 | 31.1 | 9.1 | 40.9 | 29.0 | 38.9 | 0.01 | 0.001 |
ASDAS-ESR <2.1 | Per protocol | 100 | 46.0 | 18.8 | 55.1 | 37.5 | 63.6 | 0.04 | 0.02 |
ASDAS-ESR <1.3 | Response/tolerance | 148 | 16.2 | 3.0 | 22.7 | 12.9 | 22.2 | 0.045 | 0.02 |
ASDAS-ESR <1.3 | Per protocol | 100 | 24.4 | 6.2 | 30.6 | 16.7 | 36.4 | 0.13 | 0.09 |
ASAS-PR | Response/tolerance | 179 | 11.7 | 0.0 | 12.5 | 16.7 | 18.5 | 0.03 | 0.03 |
ASAS-PR | Per protocol | 106 | 18.1 | 0.0 | 17.5 | 21.4 | 35.7 | 0.05 | 0.10 |