Fig. 5

Serum CCL19 and sCD27 levels in (relapsing) patients with granulomatosis with polyangiitis (GPA) and controls. Serum levels of CCL19 and sCD27 were determined by ELISA. a, b Patients in remission and with active disease were compared to healthy controls. c, d Patients in remission were divided into those who relapsed soon after the sampling (future relapse) and those that did not relapse for at least 1.5 years (no future relapse). In the box and whisker plots (Tukey), boxes represent the median values and interquartile range. e, f The relapsing patients were compared for two consecutive time points in remission and the ensuing active disease time point. Each line represents an individual patient. *P < 0.05, ***p < 0.001