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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: A phase III randomized study to evaluate the efficacy and safety of CT-P13 compared with reference infliximab in patients with active rheumatoid arthritis: 54-week results from the PLANETRA study

Fig. 3

Changes in efficacy parameters over time with CT-P13 and RP in the per-protocol population. a Disease activity based on DAS28-ESR. b Disease activity based on DAS28-CRP. c Disease activity based on SDAI. d Disease activity based on CDAI. e EULAR response criteria based on DAS28-ESR score. f EULAR response criteria based on DAS28-CRP score. *Proportional odds model with EULAR as response, treatment as a fixed effect, and region and CRP category as covariates. An odds ratio >1 implied that a patient who received CT-P13 had a higher likelihood of EULAR response than a patient who received RP. The proportional odds assumption implied that the relationship between each pair of outcome responses was the same. CDAI Clinical Disease Activity Index, CI confidence interval, CRP C-reactive protein, DAS28 Disease Activity Score in 28 joints, ESR erythrocyte sedimentation rate, EULAR European League Against Rheumatism, RP reference product (i.e., reference infliximab), SD standard deviation, SDAI Simplified Disease Activity Index

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