Sjögren’s syndrome-associated microRNAs in CD14+ monocytes unveils targeted TGFβ signaling

Table 1 MicroRNA microarray log2 ratios for differentially expressed miRNAs of interest

MiRNA	SjS/HC	SjS/RA	SjS/SLE	SLE/HC	SLE/RA	RA/HC
hsa-miR-346	1.04^*	1.22	0.72	0.32	0.50	-0.19
hsa-miR-629-3p	1.01^*	1.32	0.58	0.43	0.74	-0.31
hsa-miR-138-1-3p	1.01^*	1.36	0.57	0.44	0.79	-0.35
hsa-miR-324-3p	0.57	0.83^*	0.46	0.11	0.37	-0.26
hsa-miR-584-3p	0.82	1.23^*	0.57	0.24	0.66	-0.41
hsa-miR-1234-3p	0.87^*	1.38^*	0.56^*	0.31	0.82	-0.52
^#hsa-miR-3162-3p	1.34^*	1.82^*	1.06^*	0.28	0.76	-0.47
hsa-miR-4323	0.87^*	1.09^*	0.42	0.45	0.68	-0.22
hsa-miR-34c-3p	1.00^*	1.23	0.37	0.63	0.85	-0.23
^#hsa-miR-34b-3p	1.19^*	1.43^*	0.75	0.45	0.69	-0.24
hsa-miR-1228-3p	0.85^*	1.26	0.42	0.43	0.84	-0.41
hsa-miR-4254	0.89^*	1.03	0.73	0.16	0.30	-0.14
hsa-miR-765	0.25	0.92^*	0.19	0.06	0.72	-0.66
^#hsa-miR-877-3p	0.73	1.52^*	0.55	0.18	0.97	-0.79
^#hsa-miR-4701-5p	1.00	1.60^*	0.73	0.27	0.87	-0.60
^#hsa-miR-300	1.14^*	1.09^*	0.72	0.42	0.37	0.05
^#hsa-miR-609	0.98^*	0.97^*	0.71	0.28	0.26	0.01
hsa-miR-485-3p	0.71	1.06^*	0.45	0.27	0.61	-0.35
hsa-miR-466	0.45	0.13	-0.28	0.73^*	0.41	0.32
hsa-miR-1273 g-3p	-0.22	-0.11	-0.96^*	0.74	0.85	-0.12
hsa-miR-5100	0.26	-0.35	-0.59	0.84^*	0.24	0.60^*
hsa-miR-3591-3p	0.49^*	0.66	0.15	0.33	0.50	-0.17
hsa-miR-4270	0.47	1.39^*	-0.05	0.52	1.43	-0.92
hsa-miR-4778-5p	0.57	0.91^*	-0.05	0.62^*	0.96^*	-0.34

miRNA microRNA, SjS Sjögren’s syndrome, HC healthy control, RA rheumatoid arthritis, SLE systemic lupus erythematosus
^#miRNAs selected for validation
^* P < 0.05 one-way ANOVA with Bonferroni post tests

ISSN: 1478-6362