Fig. 4

Clustering of patients with lupus nephritis using frequencies of different macrophage subsets. Patients with diagnosed lupus nephritis were clustered on the basis of the profiles of macrophage subsets in different renal compartments. International Society of Nephrology/Renal Pathology Society (ISN/RPS) systemic lupus erythematosus (SLE) classes of biopsies in each cluster are indicated using a color code (pale green class II, light green class III, olive green class IV, viridian class V). The frequencies of SLE ISN/RPS classes in the clusters are shown as the number of cases within the cluster per total number of patients allocated to this class in this study. iNOS inducible nitric oxide synthesase