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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis

Fig. 5

Tubular injury score (TSI) and glomerulosclerosis score (GSI) correlation with macrophage subtypes. TSI and GSI analyzed in renal biopsies from patients with lupus nephritis correlated with renal total, M2a-like and M2c-like macrophage invasion when analyzed by the Spearman test independently of the International Society of Nephrology/Renal Pathology Society class (a, c, e, g) and restricted to lupus nephritis (LN) class V (b, d, f, h). a Correlation between TSI in all patients with LN and total CD68-positive macrophages. b Correlation between TSI in patients with LN class V and total CD68-positive macrophages. c Correlation between TSI in all patients with LN and M2a-like macrophages. d Correlation between TSI in patients with LN class V and M2a-like macrophages. e Correlation between TSI in all patients with LN and M2c-like macrophages. f Correlation between TSI in patients withg LN class V and M2c-like macrophages. g Correlation between GSI in all patients with LN and total CD68-positive macrophages. h Correlation between GSI and patients with LN class V and total CD68-positive macrophages. Significant correlation is marked by asterisks (*p < 0.05; **p < 0.01)

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