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Table 2 Correlation between tubulointerstitial macrophage subpopulations and renal function

From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis

  Total M1-like M2a-like M2c-like
CD68+ iNOS+/CD68+ CD206+/CD68+ CD163+/CD68+
Creatinine clearance, ml/min (n = 20) r = –0.454* r = 0.064 r = –0.302 r = –0.617**
p = 0.044 p = 0.788 p = 0.209 p = 0.007
Serum creatinine, mg/dl (n = 52) r = 0.411** r = -0.012 r = 0.441** r = 0.414**
p = 0.002 p = 0.931 p = 0.001 p = 0.002
Serum urea, mg/dl (n = 34) r = 0.621** r = 0.042 r = 0.506** r = 0.611**
p < 0.001 p = 0.809 p = 0.002 p < 0.001
  1. Significant correlation *p < 0.05; **p < 0.01. iNOS inducible nitric oxide synthase