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Table 2 Correlation between tubulointerstitial macrophage subpopulations and renal function

From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis

 

Total

M1-like

M2a-like

M2c-like

CD68+

iNOS+/CD68+

CD206+/CD68+

CD163+/CD68+

Creatinine clearance, ml/min (n = 20)

r = –0.454*

r = 0.064

r = –0.302

r = –0.617**

p = 0.044

p = 0.788

p = 0.209

p = 0.007

Serum creatinine, mg/dl (n = 52)

r = 0.411**

r = -0.012

r = 0.441**

r = 0.414**

p = 0.002

p = 0.931

p = 0.001

p = 0.002

Serum urea, mg/dl (n = 34)

r = 0.621**

r = 0.042

r = 0.506**

r = 0.611**

p < 0.001

p = 0.809

p = 0.002

p < 0.001

  1. Significant correlation *p < 0.05; **p < 0.01. iNOS inducible nitric oxide synthase