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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis

Fig. 2

Patients with microscopic polyangiitis (MPA) had lower reactive oxygen species (ROS) formation compared with patients with granulomatosis with polyangiitis (GPA) or eosinophilic granulomatosis with polyangiitis (EGPA). ROS production was measured by flow cytometry after ex vivo activation of peripheral blood PMN with phorbol 12-myristate 13-acetate. Patients with anti-neutrophil cytoplasmic antibodies associated vasculitides were divided based on disease characteristics into EGPA, GPA or MPA. The amount of ROS produced is shown as geometric mean fluorescence intensity (geoMFI). The Kruskal-Wallis test with Dunn’s multiple comparison test was used to calculate the level of significance. Line represents the median value of each dataset

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