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Table 2 Baseline chemokine levels in seropositive and seronegative RA patients. Values are presented as mean with standard deviation. P values were determined by Wilcoxon ranked sum test

From: Baseline CXCL10 and CXCL13 levels are predictive biomarkers for tumor necrosis factor inhibitor therapy in patients with moderate to severe rheumatoid arthritis: a pilot, prospective study

 

IgM RF+ (n = 16)

IgM RF- (n = 13)

p value

CXCL10 (pg/ml)

510.2 ± 465.2

400.4 ± 525.3

0.16

CXCL13 (pg/ml)

371.6 ± 649.0

40.3 ± 55.6

0.02*

CCL20 (pg/ml)

9.7 ± 10.3

23.8 ± 30.5

0.09

 

Anti-CCP+ (n = 15)

Anti-CCP- (n = 14)

p value

CXCL10 (pg/ml)

557.3 ± 458.0

357.8 ± 512.9

0.02*

CXCL13 (pg/ml)

396.6 ± 663.8

37.2 ± 54.4

0.005*

CCL20 (pg/ml)

9.6 ± 9.9

22.9 ± 29.7

0.12

  1. IgG immunoglobulin G, RF rheumatoid factor, CXCL10 C-X-C motif chemokine 10, CXCL13 C-X-C motif chemokine 13, CCL20 C-C motif chemokine 20, anti-CCP anti-cyclic citrullinated peptide
  2. *p < 0.05