Fig. 4From: Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodiesThe anti-citrullinated protein antibody (ACPA) response is stronger in CEP-1/homocitrullinated CEP-1 peptide (carb-CEP-1) double-positive rheumatoid arthritis (RA) than in CEP-1 single-positive RA. Anti-CEP-1 IgG (a), anti-CCP2 IgG (b), and the number of ACPA fine specificities (c) were compared between the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) cohort RA CEP-1+/carb-CEP-1- and CEP-1+/carb-CEP-1+ subsets (****p < 0.0001). Data in a and c were generated using the immuno solid-phase allergen chip multiplex assay (ISAC) microarray; data in b were generated by ELISA. AU arbitrary unitsBack to article page