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Table 2 Association between HLA-DRB1 SE alleles and RA in subgroups of patients, divided based on the presence/absence of anti-CEP-1 and anti-carb-CEP-1 antibodies

From: Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

CEP-1/carb-CEP-1

SE

ORa (95 % CI)

None

Any

Controls

959 (49.87)

964 (50.13)

Reference 1.0

–/–

468 (37.23)

789 (62.77)

1.69b (1.46, 1.97)

+/–

70 (13.65)

443 (86.35)

6.58b (5.01, 8.65)

–/+

20 (32.79)

41 (67.21)

2.07b (1.19, 3.61)

+/+

36 (8.91)

368 (91.09)

10.42b (7.28, 14.90)

  1. SE shared epitope, CEP-1 citrullinated α-enolase peptide-1, carb-CEP-1 carbamylated CEP-1, CI confidence interval, RA rheumatoid arthritis. aOdds ratios (OR) were adjusted for age, gender and residential area. bStatistically significant ORs
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Arthritis Research & Therapy

ISSN: 1478-6362

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