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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study

Fig. 1

Increased arterial TBR in RA patients on anti-TNF therapy. Quantification of the 18F-FDG uptake as the maximum target-to-background ratio (TBR) (a, c) and TBR in the most diseased section (MDS) (b, d) in the ascending aorta revealed that RA subjects in stable remission have levels of arterial wall inflammation comparable to healthy controls (a, b). However, we found increased uptake in RA patients with anti-TNF treatment (n = 13) versus RA subjects on DMARDs (n = 10) and controls (n = 17). p values are adjusted for age, gender, BMI, current smoking and systolic blood pressure, * = p < 0.05, ** = p < 0.01. DMARD disease-modifying antirheumatic drug, MDS most diseased segment, RA rheumatoid arthritis, TBR target-to-background ratio, TNF tumor necrosis factor

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