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Table 2 Logistic regression analysis regarding secretory anti-cyclic citrullinated protein antibodies in patients with early rheumatoid arthritis

From: Circulating secretory IgA antibodies against cyclic citrullinated peptides in early rheumatoid arthritis associate with inflammatory activity and smoking

Variable

SIgA anti-CCP

Unadjusted

Adjusted

Positive

Negative

p value

OR (95 % CI)

p value

OR (95 % CI)

Ever smoking

49/63 (78 %)

94/156 (60 %)

0.015

2.31 (1.18–4.53)

0.027

2.19 (1.01–4.37)

One or two SE alleles

51/63 (81 %)

130/156 (83 %)

0.674

0.85 (0.40–1.81)

0.819

0.91 (0.42–2.00)

Female sex

44/63 (70 %)

117/156 (75 %)

0.434

1.30 (0.68–2.48)

0.814

1.09 (0.55–2.14)

Age at inclusion, years

58.7

52.6

0.002

1.04 (1.02–1.07)

0.005

1.04 (1.01–1.07)

  1. SE Shared epitope, SIgA secretory immunoglobulin A, CCP cyclic citrullinated protein
  2. Adjusted values are adjusted for all other variables in the table