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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: B cell depletion therapy upregulates Dkk-1 skin expression in patients with systemic sclerosis: association with enhanced resolution of skin fibrosis

Fig. 1

Dickkopf-1 (Dkk-1) is expressed in the normal colon and skin. Dkk-1 expression in a section from a positive control (normal colon) (a, b). Note the cytoplasmic expression in the basis of crypt epithelium (black arrows). Streptavidin biotin peroxidase: magnification × 20 (a), × 400 (b). Dkk1-expression in a section from normal skin (c, d). Dkk-1 is clearly expressed at the epidermis (black arrows), appendices (green arrows) and spindle-like cells (red arrow). Streptavidin biotin peroxidase: magnification × 20 (c), × 400 (d)

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