Fig. 6From: B cell depletion therapy upregulates Dkk-1 skin expression in patients with systemic sclerosis: association with enhanced resolution of skin fibrosisCirculating factors do not participate in Dickkopf-1 (DKK1) gene upregulation following rituximab (RTX) treatment. DKK1 gene expression in fibroblasts treated with serum obtained from patients with systemic sclerosis (SSc) prior to RTX treatment was similar to DKK1 gene expression in fibroblasts treated with serum obtained from patients with SSc following RTX treatment: a normal fibroblasts; b fibroblasts from patients with SScBack to article page