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Table 3 Line immunoassay (LIA) reactivity of antibeta2-glycoprotein I (aβ2GPI) domain 1 (D1) negative-D4/5 positive and D1 positive-D4/5 negative sera from patients (Pts) with antiphospholipid syndrome (APS)

From: Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers

  

aPL IgG reactivity by LIA (OD)

 

aβ2GPI reactivity profile

Pt #

aCL

aPA

aPC

aPE

aPG

aPI

aPS

aAnV

aβ2GPI

aPT

aD1 negative-aD4/5 positive

1

0

0

0

0

0

0

0

0

20

0

 

2

0

0

0

0

0

0

0

0

30

0

 

3

0

17

0

0

0

0

0

0

0

0

 

4

0

0

0

0

0

0

0

0

27

0

 

5

0

0

0

0

0

0

0

0

34

0

aD1 positive-aD4/5 negative*

6

108

80

0

0

0

0

109

0

97

0

 

7

121

107

0

35

84

94

116

44

121

83

 

8

87

45

0

0

41

58

92

0

65

0

 

9

111

68

0

0

85

91

101

0

98

37

 

10

136

107

0

0

109

117

131

33

123

80

 

11

99

66

0

0

49

69

93

0

86

0

 

12

136

104

0

0

99

94

121

56

123

82

 

13

116

83

0

0

100

106

126

0

118

33

 

14

135

121

0

0

91

106

121

0

116

50

  1. Results of antiphospholipid (aPL) IgG are expressed as optical density (OD) values whereas OD values equaling or above 50 were scored positive (positive values in italics). aAnV antiannexin V, aCL anticardiolipin,aPA, antiphosphatidic acid; aPC, antiphosphatidylcholine; aPE antiphosphatidylethanolamine, aPG antiphosphatidylglycerol, aPI antiphosphatidylinositol, aPS antiphosphatidylserine, aPT antiprothrombin. *P = 0.0005 vs aD1 negative-aD4/5 positive