Skip to main content

Table 3 Line immunoassay (LIA) reactivity of antibeta2-glycoprotein I (aβ2GPI) domain 1 (D1) negative-D4/5 positive and D1 positive-D4/5 negative sera from patients (Pts) with antiphospholipid syndrome (APS)

From: Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers

   aPL IgG reactivity by LIA (OD)  
aβ2GPI reactivity profile Pt # aCL aPA aPC aPE aPG aPI aPS aAnV aβ2GPI aPT
aD1 negative-aD4/5 positive 1 0 0 0 0 0 0 0 0 20 0
  2 0 0 0 0 0 0 0 0 30 0
  3 0 17 0 0 0 0 0 0 0 0
  4 0 0 0 0 0 0 0 0 27 0
  5 0 0 0 0 0 0 0 0 34 0
aD1 positive-aD4/5 negative* 6 108 80 0 0 0 0 109 0 97 0
  7 121 107 0 35 84 94 116 44 121 83
  8 87 45 0 0 41 58 92 0 65 0
  9 111 68 0 0 85 91 101 0 98 37
  10 136 107 0 0 109 117 131 33 123 80
  11 99 66 0 0 49 69 93 0 86 0
  12 136 104 0 0 99 94 121 56 123 82
  13 116 83 0 0 100 106 126 0 118 33
  14 135 121 0 0 91 106 121 0 116 50
  1. Results of antiphospholipid (aPL) IgG are expressed as optical density (OD) values whereas OD values equaling or above 50 were scored positive (positive values in italics). aAnV antiannexin V, aCL anticardiolipin,aPA, antiphosphatidic acid; aPC, antiphosphatidylcholine; aPE antiphosphatidylethanolamine, aPG antiphosphatidylglycerol, aPI antiphosphatidylinositol, aPS antiphosphatidylserine, aPT antiprothrombin. *P = 0.0005 vs aD1 negative-aD4/5 positive