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Table 1 Characteristics of patients with early rheumatoid arthritis (RA) and healthy controls (HC)

From: MicroRNA-125b: association with disease activity and the treatment response of patients with early rheumatoid arthritis

 

Early RA

HC

Number

58

  

54

Sex, female/male, n

42/16

  

41/13

Age, years

54.93 ± 16.18

  

50.87 ± 15.11

Disease duration

<6 months

   

Treatment after 3 months

    

 Glucocorticoids

46

   

 Methotrexate

49

   

 Leflunomide

1

   

 Sulfasalazine

4

   

 Hydroxychloroquine

2

   

Clinical characteristic

Baseline

3 months

6 months

 

 RF IgM positivity, %

52

NA

NA

NA

 Anti-CCP positivity, %

66

NA

NA

NA

 DAS28

5.56 ± 1.56

3.05 ± 1.42

2.86 ± 1.25

NA

 CRP, mg/l

9.16 (0.30, 152.20)

3.10 (0.21, 23.85)

2.83 (0.24, 44.44)

1.02 (0.22, 4.36)

 ESR, mm/h

27.00 (4.00, 107.00)

15.50 (2.00, 54.00)

14.00 (2.00, 74.00)

NA

  1. Data are expressed as the mean ± SD or median (range) according to the distribution. Anti-CCP anti-citrullinated antibodies, CRP C-reactive protein, DAS28 disease activity score, ESR erythrocyte sedimentation rate, HC healthy controls, NA not analyzed, RF rheumatoid factor