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Table 2 Percentage of patients and controls positive for IgG, IgM, and IgA isotypes within antibodies against UH-RA.1 and UH-RA.21

From: The isotype repertoire of antibodies against novel UH-RA peptides in rheumatoid arthritis

  Anti-UH-RA.1 antibodies Anti-UH-RA.21 antibodies
Number of different isotypes present Total (n = 463) RA (n = 285) RC (n = 88) HC (n = 90) Total (n = 463) RA (n = 285) RC (n = 88) HC (n = 90)
0 333 (72) 203 (71) 62 (70) 68 (76) 305 (66) 182 (64) 55 (63) 68 (76)
1 104 (22) 66 (23) 21 (24) 17 (19) 116 (25) 72 (25) 26 (30) 18 (20)
2 22 (5) 14 (5) 3 (3) 5 (6) 36 (8) 27 (9) 6 (7) 3 (3)
3 4 (1) 2 (1) 2 (2) 0 (0) 6 (1) 4 (1) 1 (1) 1 (1)
  1. HC healthy control subjects, RA patients with rheumatoid arthritis, RC rheumatic control subjects
  2. The presence of anti-UH-RA.1 and -UH-RA.21 antibodies of the IgG, IgM, and IgA isotype was determined in 285 patients with RA, 88 RC, and 90 HC. Data are presented as absolute number (percent). Contingency analyses for individual isotypes or the number of isotypes did not show any significant differences between the three study populations