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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Antibodies directed against endogenous and exogenous citrullinated antigens pre-date the onset of rheumatoid arthritis

Fig. 1

a Concentrations of antibodies against viral citrullinated peptides derived from Epstein-Barr-virus derived protein (VCP1) in controls, pre-symptomatic individuals and patients with rheumatoid arthritis (RA). Grey line indicates the mean of the concentrations; ***p < 0.001. b Concentrations of anti-VCP2 antibodies in controls, pre-symptomatic individuals and patients with RA. Grey line indicates the mean of the concentrations; ***p < 0.001. c Concentrations of antibodies against histone 4-derived citrullinated peptides (HCP1) in controls, pre-symptomatic individuals and patients with RA. Grey line indicates the mean of the concentrations; ***p < 0.001. d Concentrations of anti-HCP2 antibodies in controls, pre-symptomatic individuals and patients with RA. Grey line indicates the mean of the concentrations; ***p < 0.001. AU arbitrary units

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