Fig. 1

Schematic diagram illustrating the suppression of the interferon (IFN) pathway in the skeletal muscle of patients with PM or DM after immunosuppressive treatment determined using the Ingenuity Pathways Analysis knowledge database. Green represents significant downregulation of the gene expression, red implies significant upregulation, and grey specifies changes that did not reach the defined cutoff. A higher intensity of the colors suggests a higher degree of change. No color indicates no presence of this particular gene in our data set