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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile

Fig. 2

Clinical outcome of collagen antibody-induced arthritis (CAIA) is independent of FcεRIβ+-cells. a Progression of CAIA-induced arthritis in both mast cell-competent and -depleted RMB-DBA/1 mice. (n = 6/group) (b) Mast cell numbers in the ankle joint of PBS- and DT-injected RMB-DBA/1 mice. (n = 6/group) (c) FACS analysis for common peripheral leukocytes in both groups (n = 6/group). AUC area under the curve, DT diphtheria toxin, PBS phosphate-buffered saline

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