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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis

Fig. 2

CIA development in LNT-Igk-Ctrl and LNT-Igk-CII mice. a Arthritis frequency and b clinical severity after CIA induction in LNT-Igk-Ctrl and LNT-Igk-CII mice. c Histopathological evaluation of synovitis and joint erosions at day 40 after CIA induction (n = 10 per group, one of three experiments is shown). Indicated P values were determined using Fisher’s exact test for nominal data, linear regression to compare the severity of arthritis (shown as mean ± SD) and a non-parametric test for categorical data. *P < 0.05; **P < 0.01; ***P < 0.001

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