IC50 (μM) | MCP-1 | IL-6 |
---|
DMF | 8.8 | 12.2 |
Sulforaphane | 2.0 | 3.9 |
Prednisolone | >100 | >100 |
-
aConcentrations of 50 % inhibition (IC
50
) of MCP-1 and IL-6 production were calculated from sigmoidal inhibition curves presented in Fig. 3. The IC50 values were obtained from three individuals
-
DMF dimethyl fumarate, HRMC human renal mesangial cell, IL-6 interleukin-6, MCP-1 monocyte chemoattractant protein-1, Nrf2 nuclear factor erythroid 2-related factor 2, TNF-α tumor necrosis factor alpha