Arthritis Research & Therapy

Table 1 Dialysate and plasma levels (pg/mL) of cytokines as well as frequency (%) of detectable samples in 24 patients with fibromyalgia (FMS) and 27 healthy controls (CON) before and after 15 weeks of resistance exercise twice per week, as well as the P value for within-group comparison (Wilcoxon test)

From: Effects of 15 weeks of resistance exercise on pro-inflammatory cytokine levels in the vastus lateralis muscle of patients with fibromyalgia

		FMS		P value	CON		P value
		Before	After		Before	After
IL-1β
Dialysate
	Detectable	48	44		41	34
	Level	0.10 (0.13)	0.05 (0.16)	0.522	0.06 (0.17)	0.01 (0.16)	0.479
Plasma
	Detectable	70	83		89	96
	Level	1.13 (3.55)	1.23 (1.86)	0.823	1.23 (1.40)	1.54 (1.33)	0.845
IL-6
Dialysate
	Detectable	97	95		98	100
	Level	81.1 (131.7)	100.4 (236.3)	0.540	156.4 (196.9)	107.0 (173.5)	1.000
Plasma
	Detectable	91	100		96	96
	Level	1.60 (1.48)	2.35 (2.14)*	0.831	1.31 (1.43)	1.41 (1.24)	0.556
IL-8
Dialysate
	Detectable	95	91		98	99
	Level	37.5 (75.6)	42.2 (71.6)	0.838	61.0 (101.4)	61.7 (58.0)	1.000
Plasma
	Detectable	91	87		74	78
	Level	1.66 (2.10)*	1.22 (3.19)	0.136	0.47 (1.61)	0.56 (1.11)	1.000
TNF
Dialysate
	Detectable	67^#	67^#		93	94
	Level	0.16 (0.18)*	0.19 (0.25)*	0.831	0.27 (0.23)	0.26 (0.17)	0.556
Plasma
	Detectable	100	100		100	100
	Level	4.27 (1.70)	3.79 (3.67)	0.831	3.72 (2.68)	3.56 (2.31)	1.000

The dialysate levels represent the average of 5 samples obtained during microdialysis (140-220 min), which included 20 min of dynamic exercise. Dialysate and plasma levels are presented as median (interquartile range)
Between-group comparisons: *P < 0.05 (Mann-Whitney U test) ^# P < 0.001 (Chi square test)
IL interleukin, TNF tumor necrosis factor beta

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